The only truly nihilistic anime (yet). It portrays humanity as it is...

Cyberpunk anime about consciousness and what it means 'to exist'

Cryptic anime about impermanence and what it means 'to be'

BEST FANTASY ANIME EVER MADE!!!!!!!!!

The only truly poetical anime I have ever seen.

Slice of life / Sci-fi anime about multiculturalism.

Slice of life / Post-apocalyptic anime about culture.

Vampire's immortality as the raw rejection of an apathetic stagnation.

Vampire's inmortality as the unbearable emptiness of an unavoidable fate.

Vampire's inmortality as the timeless boredom of an eternal return.

Space Opera anime about the value of life having no exceptions...

Post-apocalyptic anime about death and what it means to be alive.

A.I. Idol anime about purpose and what it means having something to live for.

Cyberpunk anime about identity and what it means to be human.

Virtual Reality anime about social isolation in the digital era.

Mecha anime about the impact of human connection, on others and oneself.

Gore anime about the tragedy of The Human Condition.

Horror anime about the wickedness of humanity.

Horror anime about negative human emotions.

Samurai anime about 'The Hero's Journey'

Time Travel anime about causality and the ARROW OF TIME.

Space Jazz anime about nostalgia and the inevitability of change.

Mecha anime about the recurrence of human conflicts through history cycles.

Viking anime about violence, suffering, forgiveness and redemption.

Isekai anime about the futility and cruelty of wars.

I don't even have words for this one. 

Mangaka sure knows how bleak and twisted we human beings can be...

And I'm pretty sure The Abyss is Hell itself.

Slice of Life anime about Philosophical Absurdism.

Fantasy anime with the most outstanding worldbuilding I have ever seen.

It feels like watching again an adventure show when you were a kid!!

Fantasy anime about depersonalization and objectification.

Fantasy anime about questioning one's place in the world.

Surreal anime about personality: emotions, thoughts, and memories.

Metaphysical anime about escapism and existential dread:

Is there any meaning in the choices we've made along the way as we keep going on?

Surreal anime about coping with regret and remorse.

Noir anime about addiction, alienation and anxiety. 

Slice of life anime about SUICIDE.

Surreal anime about loss, grief and trauma.

Noir anime about the comedy of The Human Nature.

Satou is probably the best portrait of a psychopath in any anime ever.

(Yes, even better than those on Classroom of the Elite, Monster or Psycho-Pass)

MOB IS MY HERO!

BEST SHONEN EVER!!!

PERFECTION

KAGUYA IS THE ULTIMATE WAIFU <3

BEST ROMCOM EVER!!!

PERFECTION

Dunno which genre girls music band is, but this one is the greatest of them.

This is THE meta anime: an Anime about making Anime.