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The franchise centers on two friends: a naive weasel who likes cute and round things, and a dormouse who plays innocent. Together, they spend their days playing and having fun in short stories set in Nagano Prefecture.
Michi and her parents have just move into the Happiness House, a bizarre neighborhood built atop a giant tree. As Michi ventures into her new room, a strange nut falls from one of the tree branches on the ceiling, revealing a small creature inside called Nanami-chan. The two quickly become good friends and begin to explore the Happiness House, discovering its secrets, meeting the neighbors, and teaching Nanami about the world, from daifuku to astronomy.
Having settled into their new home, Michi and Nanami continue to live their everyday lives alongside all the other residents of the Happiness House. With a host of mini adventures around every turn, from taking care of a hamster and going on a diet, to Nanami running away from home with Eiffel and Kyu and protecting the house from a thief in his own unique way, there’s never a dull moment in the lives of the Aoba family.