Genshiken is about a buch of college student otakus. You really get the slice of life experience and also the growth of the characters.

Although there are children in this anime, I am very much of the opinion that the adult theme makes it unsuitable for children.The main character has a very 'grown up hero' attitude and makes for a very good whatch as the relationships between characters are bonds forged through adversity.

This anime is about college students in an arts college.Whatching their everyday struggle to find what they are meant to do in life is very rewarding.

this sci-fi story follows a self described mad scientist in his quest to discover time travel, with all the good and bad consequences that ensue.

Following excentric music college student Noda Megumi - Nodame that float through life in need of a passion when she encounters traumatized piano college student Chiaki Shinichi that dreams of becoming an orchestra conductor but cannot make the trip abroad.Whatching these characters evolve make for a great story.

Good depiction of the world of rakugo while making the characters apear very human, with all their falws and greatness.

Very good detective stories

A story of an otaku that happens to work in the military when the known world collides with a new world that seem right out of a fantasy game, he is decided to makes the most of his time!

A very noir story about a rookie policewoman working with a team in search of people whose mental pattern - psycho-pass - is that of criminals.

nice adaptation on the drama story of the count of monte cristo

in this world where supernatural beings and phenomena are side by side with humans, this mushi-shi, like a biologist for supernatural bugs wanders around looking for a place to belong.

An adult shodo master that knows nothing about the world. makes for an endearing story.

This anime is about the world of shogi seen through the eyes of a young man with no place to belong. When one day he is taken in by this warm family, his life slowly begins to change

Very grown-up story of a love on rainy days

this behind the scenes story of hokusai's daugter wil captivate you

Acton filled sci-fi story with a philosofical twist... what makes us humans?

Actoin filled, old west-inspired future story of very broke bounty hunters!

what if everything in life could be soved with a game?

In this dystopian future world we follow a team of special forces people that have been enhanced to became partly androids.

this enhancement... where does it stop?

Well no fooling anyone this is BL... but the show buisiness setting is very good!

Very otaku"ish" girls pulled into the fashion world by a crossdressing ikemen. the combination is genious! The story is endearing and the visuals from this anime are gorgeous!

In a world where soe people have powers, this is the working of a detective/bodyguard agency

Fashion College students enroll a very serious high school girl as their model.

Well... College boys... cheering... 

This story is like a psychotropic experience. where every character is crazyer than the next. Ah and by the way they all live off the grid under a bridge on the river arakawa.

deranged story about a paranoid shut-in adult falling in love with a real life school girl

briliant story with a great sense of humor about a human weapon boy and his girl wielder.

This will take you space traveling!

ronin samurai meets action filled comedy, what more do you want?!

ok this anime is more a moe show than a mature one I'll give you that but it very much fits in the 'slice of life' category

This anime about the arrival of a lifeform from outside our universe has a sense of mistery that enthralls you. With the very put together government official main caracter, Shindo Koujirou, being a genious negotiator, you never expect what might come next.

ever seen he TV show Lost?

This anime about a young lawyer's troubles is a genre suitable far all ages.

Seriously making anime is no easy feat! This anime will take you through the grueling life of an anime making team

Otaku come in all shapes and sizes and this one is about a girl over 30 addicted to MMORPGs

a sort of parallel-world warring states era style.

BL romance stories in a manga editing firm

a home tutor of royal children - ikemen in an entertaining kingdom.

When your reality falls short of your expectations and dreams, the only way to go is METAL!

Who makes dictionaries? if you've ever asked yourself that, then this anime is for you! If not, give it a try anyway, this might have you in for a good surprise!

Ecchi much?

Although i didn't want to include short format anime, this one is about two adults having a naughty relationship ah and one of them is a priest and the other one is his childhood female friend

playing house with a supernatural fox kid

this is a slice of life/romance blend with a very good sense of humor

This android assisted future will make you cry.

Nice detailed stories involving precious stones