If you're looking for manga similar to Pearl and Vice, you might like these titles.
Kokoe Kusunoki is a teenager who loves taking care of children. In order to work towards her dream of becoming a childcare worker, she regularly helps out at her family's preschool. One day, her high school's idol, Mahiro Natsuna, gets a job working part-time with her at Kusunoki Preschool, and Kokoe is drawn to his shared passion for working with kids. If only they could get along.....
Momoko Sugisaki works for the Little Snow Sick Child Care Service, providing in-home day care for sick children. She has a hard time making pleasant facial expressions, and she struggles with the question of when it's okay to break the rules if it's what the child needs. As she grows through her personal challenges, she is able to make a difference in the lives of the young children and parents who depend on her.
God has been dead for some time, and the angels in heaven have decided it is time to find a replacement. Though very reluctant, the angel Rain has been chosen as one of the four candidates in for consideration to become the next God. He and the four other candidates will decend to earth for one year so that they may perform a test to determine their suitability for the position, with the ability to reveal their true identity to one human being of earth.
Honoka Sawada is a lonely fourteen year-old girl who has no friends at school and spends her nights alone - that is, until one day she wakes up to find a fire-breathing baby named Mao in her bed! After meeting the mysterious principal of the Chibi Devil nursery, Honoka learns that Mao is in fact a demon baby, and she is now his surrogate mother. With only her anime-obsessed childhood friend Kyou and his hot-headed pal Shin to rely on, Honoka decides she can’t possibly look after a child and asks the principal to find a replacement parent. Now, until a substitue can be found, Honoka will have to spend the next month looking after Mao, but will she be able to cope, especially when a strange pair of teenagers are intent on taking Mao for themselves...
Hana is a pretty serious young woman who is not interested in love and who lives in a religious sanctuary in Japan. One fine day, she finds a baby in the garden of the complex. Abandoned at the foot of a cherry tree, it holds out its arms to him; the young woman then collects it to take care of it, and suddenly, the charming Koba also appears at the temple. Hana, not really gifted with feelings, does pretty well with the young child, but can she really pretend to be in a relationship with Koba to raise him?
Heisuke is a young man who was left in charge of taking care of his little cousin Aki for a day. Being an only child who usually stays at home alone, Aki is quiet, reserved, and will go out of his way not to make trouble for others. As they spend more time together, Aki begins to grow very attached to Heisuke, especially since Heisuke's hobby is to make sweets and desserts. The quiet Aki eventually opens up to Heisuke, and Heisuke in return teaches Aki that sometimes it's all right to be selfish and say what you really want to do.