If you're looking for manga similar to Enji-sama no Yutoori, you might like these titles.
After losing her mother to a tragic accident, 6-year old tomboy, Michiru, finds a suspicious person moving into her precious home: her dad’s giant younger brother Kouji, the “Beard Gorilla”. While awkward at first, it doesn’t take long for the two to develop a familiar bond that looks more like that of a brother and a sister, than that of niece & uncle.
The story follows Iku Fukuda, who likes working with kids, so he gets a job at a day care center. When he realizes there's a gap between his expectations and reality, he quits after 2 months. But Fukuda doesn't give up on his love of working with kids.
Even though Rumi now has become a mother, days of observing Makuru, her son and "his" childlike enthusiasm are not over yet. Meanwhile, the father is...?
High school student Shuto is looking forward to being free and at ease while his parents are working overseas. Only problem is, things don't exactly go as planned when he finds a 5 year old girl in his house. As it turns out, the girl's mother is a colleague of his parents and is traveling overseas with them and has left her daughter in his care for the next 3 months!!