One day on the peaceful world of Jewel Land, Ruby is entrusted with the magical Jewel Box given to her by Queen Jewelina. Given a mission to make friends, she is entrusted to fill the jewel box with magic jewels, but, also needed to attend the Jewel Academy and open a shop called the Jewelpet Cafe. However, things didn't go well as expected as the cafe is considered abandoned and needs a lot of work for them to prosper and to reach that goal Ruby is expecting. But when she met three junior high school students named Chiari Tsukikage, Nene Konoe and Ruruka Hanayama, she decides to make friends with then and accepted their help on managing the Jewelpet Cafe. Now, they all decide to work together for the cafe to prosper and to stick together through good and bad luck but at the same time, prevent the Jewel Box from being stolen. Ruby and Chiari's lives were about to change forever...for the better or worse.