In a dystopic future, the Mir space station fell from space for an unknown reason -- bringing with it a death sentence for every man on Earth. Women have adapted to the loss and for the most part, are living their lives in peace, but bio terrorism is on the rise and the women of Japan need protectors. Hitomi Landsknecht is the leader of a group of such protectors, but she and her comrades will soon discover the new technology known as "ICE". Mysterious and unknown, it is somehow related to males being born again – an occurrence which may signal the rise of humanity once again. However, the technology may also create a monster and destroy what is left of womankind. Can the remaining females change their destiny or will it be too late?