If you're looking for anime similar to Astro Boy: Shinsengumi, you might like these titles.
Metropolis is a grand high-tech city-state populated by humans and robots alike. It is in these streets that Detective Shunsaku Ban and his sidekick Kenichi search for the rebel scientist Dr. Laughton who unbeknownst to them, is developing a super android named Tima as a tool for the Duke of Metropolis. What starts out as a normal case turns into mayhem as the scientist is murdered, and the true plans of the Duke are finally revealed...
Haruka, the only known survivor of a cataclysmic global war, has taken refuge with a diverse group of sentient robots with distinct personalities. They attempt to survive in the desolate post-war environment; however their supplies are limited and the military robots are still active and hostile. Haruka remains optimistic that other humans may have survived the war, but their persistent search efforts have failed to locate any survivors. Is she destined to live her life without any human contact?
Astro Boy confronts Blue Bon and tries to convince him to change his mind about the humans. But Blue Bon misunderstands, assuming that if Astro Boy does not agree then he is an enemy. Blue Bon hates humans because they broke apart his family (Maria and Tonto). A battle begins between the two after Astro Boy fails to convince Blue Bon that they aren't each others' enemy.
The Shinki go through various evaluations to check on their general health. Meanwhile, a plot to steal an AI system begins to hatch…
Cutey Honey is an android created by Prof. Kisaragi. Within her is the 'Fixed System of Air Elements', a device that can create anything out of air. The evil organization Panther Claw desires this device. While trying to steal it, they kill Prof. Kisaragi. Now furious, Honey makes a vow to get revenge, and destory the Panther Claw.