If you're looking for anime similar to 12-Sai: Chiccha na Mune no Tokimeki 2, you might like these titles.
To those of you out there who never could say "I love you" — This story is about ordinary highschoolers and how love makes them fired up, shaken, laugh, cry, and hurt. Whether things go well or not, this story of adolescence and romance will show you how they spend their precious youth. Every character is the main character here, and you're sure to find one you can sympathize with.
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Both series explore a naive ideal to love. The characters of each series have trouble processing their emotions, but work with their respective castmates to come to understand this difficult thing called "love". The ages of the cast are relatively similar, however 12-sai frames the characters as quite a bit younger.
Mikiko Amane is an elementary-school girl who has transferred schools many times. Because of this, she stopped making friends or getting deeply involved with people, since she knew she would move again soon. She had lived her life with a cool and uninterested personality, but at her new school, she meets a boy with a cat face. She's so interested in him, she just can't help herself.
Puberty is an embarrassing, trying time for a child. Your body changes, you start to have feelings for the opposite sex, and more than anything, you are confused and bewildered about what’s happening to you. Tsubomi, Rea, Saya and a group of other fifth-grade students are being faced with this difficult event, and will experience the joys and horrors of it together. From learning about the difference between the male and female bodies, to experiencing a first kiss, to discovering the cause of pregnancy and even getting a first period, Tsubomi and her friends will finally learn what it means to be a grown up.
When energetic fourth grader Asari and her sister – a sixth grader at the top of her class argue over the smallest things, only their mother can stop them.
Nijika Kohinata is a tall cheerful young girl who dreams of one day being an actress like her mother.
Tsubasa Sonokawa is a 15-year old high school girl who fell in love with her upperclassman when he saved her after she fainted at the train station from anemia. She thought it was a meeting of fate, and visited him at his class every day. However, he told her that her feelings were "heavy," and he dumped her. She once again meets a boy after taking over her friend Yuri's job as boy's basketball team manager. She learns that she might have more of a connection with this boy named Aki than she first thought.
Short, athletic Hikaru Suzuki has just started his first year at junior high school, and things couldn’t be more eventful. He’s reunited with his sisterly childhood friend Chihiro Itou and had a glance at the wealthy, egotistical other Suzuki named Shinobu. However, most importantly, Hikaru’s first day of school yields another life-changing encounter: his first meeting with the shy would-be actress Sayaka Hoshino…