Witchblade, based on an American comic of the same name is, to summarize its premise, about some weird bracelet thing that doesnt come off, gives the wearer a lot of power, makes people attracted to that power, and slowly kills the wearer.
However, interestingly enough, the story is not actually based on revealing on the sci-fi portion of the premise at all but on the characters instead, namely Aname and her daughter Rihoko. In that way, the story progress into a much more indearing type of series rather that action, ecchi, or sci-fi about a mother working to protect her daughter. While the Witchblade still plays an important role in advancing the plot with its numerous related futuristic plot elements, it is not the prime focus.
The anime is pretty good and the ecchi in my opinion is well received; it has low significance but doesnt take away from the anime unless you are the type to judge stories based on things like that (which is strange but whatever floats your boat).
The openings and ending suck and the music is fairly bland.
This anime is pretty shounen due to its art style but it should be interesting for everyone.