Gintama was one of the first animes I started to watch after Bleach, Naruto and One Piece, so it was very hard for me to understand some of the 'referance style' jokes that Gintama uses. Aside from this confusion, I still managed to love Gintama SO much! I was laughing out loud beginning to end on most episodes! Then just when the comedy can't get any better, it throws you into some AMAZING fight scenes! Gintama for me features some of the very best fight scenes out of the many anime I have seen.
I really recommend watching this to anyone, you might find it confusing like I did at first but after that phase you won't be able to stop watching!