4.337 out of 5 from 71 votes
Kirihito Osanai is a talented doctor with a successful career and a beautiful fiancée. However, once he's sent to a remote village to investigate a rare disease known as Monmow, his life quickly changes forever. After spending time with the infected patient, Kirihito begins to show the symptoms of the deadly disease - his body physically changes to a dog-like form and he begins to crave raw meat; what awaits him is a slow and painful death. Thus begins Kirihito's nightmarish journey into the unknown. He's kidnapped, forced to perform as a circus freak and branded a deviant by everyone he comes across, while back home in Japan his ex-colleagues and fiancée search for what happened to him and uncover a conspiracy that shakes them to the core. Meanwhile, the search for the cause of the Monmow disease continues...
The world is never quite the same once we grow up. Villains and robots that once ran rampant in our imaginations are reduced to drawings in Manga, and our lives are distilled until there is little left but the daily grind; so it has been for Kenji. After a childhood of dreams he now runs his late father's liquor store and is raising his sister's child. The memories and friends from his early years bring him some happiness, but they become tainted as a string of murders find connections to his past. Kenji and his friends must now fight to save the future from their past and unravel the mystery of "Friend."
Ode to Kirihito and 20th aren't simialr in plot, but I definitely felt similar after reading them (NOTE: 20th is FAR better and way more epic than Ode, but Ode is also good). Call it a gut feeling, but I think you'll appreciate the similar storytelling style.