Medusa is a mysterious illness which causes the body to petrify shortly after infection, found throughout the world and steadily increasing the death toll. After losing his son to the disease, a wealthy gentleman used a large portion of his fortune to turn his medieval castle into a state of the art cryogenic facility. 160 lottery winners were chosen to be frozen until a cure could be found, one of whom is Kasumi - a twin whose sibling was not one of the chosen. Along with a group of others Kasumi awakens from her cryogenic chamber, but not to the same world she left it: prehistoric monsters roam the now-abandoned castle and eat the survivors, while endless giant thorns rise all around them. Against all odds, Kasumi and the others must now try to survive the horror of their situation and discover the truth behind what's happening, all the while waiting for the Medusa to finally claim their lives...
Natsu, Arashi and a few dozen others had gone to bed like any other night when they woke up... somewhere else. In this new post-apocalyptic future, mutated plants and animals lie in every direction and mankind is long extinct. Scientists of the past predicted that a meteorite would strike Earth and render the planet uninhabitable, so they devised a plan: they would cryogenically freeze five teams of young adults and have them revived by a computer when life is again sustainable. Seven people formed each team along with a guide specially trained to survive in the wild, and seven caches of supplies were left to be found. Together, the teams must try to survive in a new and hostile world, inadvertently finding the other survivors and clues to their circumstances along the way.
It would be impossible not to recommend these two manga for each other, though I consider King of Thorn the far superior product. Both involve cryogenically frozen people who wake up in a very unfamiliar and very messed up place, and must now struggle to survive against all odds. Both are horror, and both are good matches for each other.
Akira Sengoku and his class were traveling home from a field trip aboard Flight 357 when the plane mysteriously crashed, leaving them stranded on a hostile, prehistoric island. In this place, extinct and colossal animals run wild, quickly devouring many of the survivors and leaving the rest to fight for their lives. Alongside his childhood friend Rion and other classmates, Akira will struggle to survive in this impossible place against all odds.
A group of people find themselves in a mysterious and sometimes dangerous place, with abandoned structures filled with further mysteries. Both Cage of Eden and King of Thorn belong to the same school of storytelling as the popular US TV series Lost, although it must be said that they do a better job of keeping the audience engaged with the storyline.
On a day like any other day, Shou, his classmates and the entire elementary school were mysteriously transported to a barren wasteland filled with terror. There's no food or water, nothing in sight but an endless desert in all directions, and both the students and teachers are so terrified that they are rioting, murdering, and falling victim to their fears. With no idea of how they got there or how they'll survive, these students must work together and set forth into the unknown to discover the truth of their circumstances.
While Drifting Classroom is exponentially more graphic and disturbing, it and King of Thorn are good matches for one another. The characters find themselves in a strange place and struggle to survive against vicious enemies and hardships. Most importantly, they fit very well together horror-wise and will definitely appeal to the same audiences. There's also one spoilerific element that applies to both, but that's only a minor reason for recommending the two.
After being diagnosed with a mysterious disease, Honoka Kusakabe was put into cryostasis by the scientist Heitarou, her father. However, when she awakens it is not to her family’s loving arms – she is greeted instead by a barren world filled with vegetation and not a single human in sight, save for a dog-like robot named Haco. With his help, Honoka learns about the new world around her and searches for the answers she seeks.
Though King of Thorn is far more dark and serious (not to mention gory), both it and Haco feature a character who was put into cryostasis, only to wake up later to a much different, much less populated world.
A boat approaches a remote, uncharted island, filled with people contracted by the Kashoo company. Their mission is to perform various tasks for the company in exchange for a high fee, though soon they discover that it comes at a high cost. Each person has their own reason for coming, and not all will return. What horrors await these workers, and what is Kashoo really doing behind the scenes?
King of Thorn is one of my favorite survival mangas, and La Mosca isn't half bad either. Both involve people running from or having to kill giant crazy monsters, with plenty of horror and action to go around.