While trying to escape from Marie, a homicidal, troubled girl who's infatuated with the man, Rokusuke stumbles into an inn to hide. But little did he know that it's no ordinary inn – in fact, the establishment is run by a supernatural witch named Okami who kills those that don't pay! What's worse, Marie decides to stick around as well to become a maid, and she's determined to not let anyone else get their hands on her crush. With plenty of danger ahead, Rokusuke must survive each day, dodge Marie's advances and learn about the history of the inn and its unusual inhabitants.
Both Karakasa no Saien and The Voynich Hotel take place in a hotel\inn in which both the staff and guests are weird (in a very twisted way). If you liked one of those two, you might want to give the other one a try.