Tsukushi Makino is an average girl who attends a not-so-average school. Populated by an elite and high-classed society of students, the school is also home to the F4 - the richest boys in school who dictate the lives of both the students and the teachers. One day, Tsukushi's friend accidentally falls and knocks over the F4's mighty leader, Domyouji Tsukasa - a boy famous not only for his money, but also for striking fear into any student who looks at him the wrong way. Domyouji doesn't take being knocked over lightly, and when Tsukushi sticks up for her friend the F4 declares war. With the whole school now against her, Tsukushi works hard to show everyone that she is a ‘weed' that will no longer be trodden upon!
Besides having very similar art styles, Boys over Flowers and Tokyo Boys and Girls have some similar plot points. Settings, for example, are both placed at a private high school. While Boys over Flowers tends to focus more on bulling and money, Tokyo Boys and Girls puts more focus on relationships and love, but they have similar moods. Where Boys over Flowers is a little deeper, Tokyo Boys and Girls can get away with being a little more slapshot. They compliment each other well, and I recomend both.