In the year 2199, unrelenting attacks from the planet Gamilus have forced all life on Earth into underground dwellings and raised radiation levels to near-toxic levels. The only way to clean up all this harmful radiation is by using the Cosmo Cleaner, which the Queen of the planet Iscandar has generously offered to humanity. Unfortunately, Iscandar is 148,000 light years away, but Earth only has one year before rising radiation levels make it uninhabitable! The only vessel capable of making the journey is the battleship Yamato - a rusty relic of World War II. Can the crew of the Yamato make it to Iscandar and back before the extinction of all life on Earth?
In a far and distant future, men and women have become mortal enemies. Each living on seperate planets, an interstellar war is being fought between the two very different peoples. Hibiki, a mere 3rd class worker, finds himself in the middle of a huge space battle, facing the nemesis of mankind: Womankind!
The story is somewhat similar in Vandread and Star Blazers, as the crew of the Nirvana in Vandread is trying to rescue humanity from an imposing threat, and must venture to the far reaches of space to find what they are looking for. If you were a fan of one of these series, you should give the other a try.