Two Japanese survivors of the Khmer Rouge massacres in Cambodia vow to find a sanctuary, even if they have to build it themselves. Returning to Japan, they take seemingly opposite paths: one becomes a politician, the other a gangster. As Asami and Hojo work through the linked worlds of politics and crime in modern Japan, they don't hesitate to do anything necessary to secure their own positions and stay true to their vow. Loyal to no one else, they find their friendship increasingly tested as they rise in their chosen fields.
Brandon Heat and Harry MacDowel were best friends who lived by the law of the street, until one day they picked a fight with the wrong people and their life of freedom was suddenly taken away. With no one to turn to and nowhere to run, the choice to join Millenion, the city's most powerful syndicate, seemed like an offer they couldn't refuse. Now, amidst heartache, tragedy, and utmost betrayal, Brandon must take up the gun and help Harry climb the ranks of Millenion to succeed, in order to protect the people he loves, even if it means killing countless others in the process.
These two anime are very similar. Both portray the story of two life-long friends who support each other and buld their own futures with the underworld of yakuza/gangsters as their base to begin from, and using whatever underhanded tactics are needed to go up in the scale. The only difference on this premise is that, in Sanctuary, one of the two moves on the world of politics, but through the path of corruption nonetheless.
Watch Gungrave for a superior, longer and more fulfilling version of this same idea, but if you're already a fan of Gungrave I think you'd enjoy this hour-long yakuza flick.