If you're looking for anime similar to Saiunkoku Monogatari 2nd Series, you might like these titles. All recommendations are made by Anime-Planet users like you!
After defeating the Spirit of the Sacrea which prevented the newly born Seijuu Universe from developing, Angelique hears that the Queen of Seijuu Universe – the one who maintains the stability of nine Sacrea - has disappeared. Moreover, she cannot go back to her home universe because the dimensional corridor connecting both universes has been destroyed. The Seijuu Universe is still in danger and Angelique is left alone without the support of nine Guardians. What should the Legendary Etoile do to find the Queen and bring her back?
Looking for reverse harem animes? Look no more Angelique ~Kagayaki no Ashita~ and Saiunkoku Monogatari share many similarites, both animes are centered on a charismatic female protagonist who is surrounded by male characters.If you like one of them then for sure you will like the other one.
Disguised as a boy, Chizuru Yukimura has come to Kyoto, searching for her missing father. Soon, she stumbles across a battle between the Shinsengumi and the Furies. The Shinsengumi, who are also searching for her father, take her into their custody for safekeeping. However, there are even greater mysteries behind the whereabouts of Chizuru's father, and the Shinsengumi find that the Furies may be the least of their problems in Hakuoki Season 1!
Both Hakuouki and Saiunkoku are stories about strong female characters who are surrounded by various male characters who are historical figures. They take place in two totally different time periods, but both protagonists similarly encourage and assist the characters around them. Hakuouki does lean in a darker, supernatural direction with less romance, but I think fans of Saiunkoku would enjoy it nonetheless.
I have to repeat, what I wrote about first seasons of these series:
Both main characters Shuurei and Ritsu are working hard to succeed professionally (Shuurei has it more complicated, since she is first female to enter male dominated government; not that Ritsu has it completely easy, he has to learn lots of things about his new field of speialization) and at the same time they are refusing relentless declarations of love.