The fantasy world of Arcadia is in peril: fierce monsters known as Thanatos are sucking the life from humans, and only men known as Purifiers can vanquish them. Angelique is a young girl who attends Melrose Girls Academy and thought her life was normal, until the dashing Nyx told her that she has hidden powers within. After a brutal attack by a Thanatos, Angelique finds she is able to help in the battle and heal those who have been sucked dry; her powers are real, and she discovers she is in fact the Queen's Egg - the only female Purifier. With the help of allies such as shoot-em-up Rayne, the happy traveler J.D. and Silver Knight Hyuga, Angelique will learn about her powers and help put a stop to the Thanatos.
In Amberground, the land of eternal twilight, Letter Bees and their dingos – creatures trained to protect them – deliver mail to the general populace. However, unlike normal mail carriers, their job is perilous as they must traverse the country while fighting off the giant armored insects known as Gaichuu. One day, a Letter Bee named Gauche collects his latest delivery: a young boy named Lag Seeing, whose mother was taken under mysterious circumstances to the capital of Akatsuki. As the pair travels together, they strike up a friendship, but when they finally reach their destination Lag and Gauche part ways. Now, several years later, Lag is about to take the exam to become a Letter Bee himself so that he can meet with Gauche again and find out what really happened to his mother all those years ago. But before any of that, he must find himself a dingo...
All Renji Hiiragi wants to do is to go to school and life a normal life. However, because he is a wizard, he is forced by the elegant yet abusive protector of Earth, Anzelotte, into using his powers to fight against supernatural invaders called Emulators! Renji, along with his childhood friend Kureha and the serious Akari, are tasked with protecting Elis Shiho, who has been chosen to collect seven mystical jewels in order to protect the world against an imminent Emulator invasion. In the meantime, enemies act from the shadows in an effort to prevent them from succeeding. Can they strengthen themselves as a group enough to overcome the obstacles before them, so Renji can finally get back to his studies?
One day a girl finds hidden powers in herself and decides to use them to bring peace and happiness to the world. Although both Ellis from Night Wizard and Angelique from Neo Angelique Abyss are quite naive, they are true to their beliefs and make sure they won't stray from the chosen path. Also, they both are surrounded by friends who deeply care about them and are ready to sacrifice themselfs in order to save the girls.
On the eve of nobleman Oz Bezarius's fifteenth birthday, he and his loved ones gather to celebrate in a coming-of-age ceremony. But after Oz steps under a long-stopped clock and the hands finally move once more - thus fulfilling a mysterious prophecy - he is violently thrown into the legendary prison known as the Abyss by three cloaked intruders. Existing in another dimension, the Abyss is home to lifeforms born within its walls known as Chains; these beings can only live in the real world if they make contracts with humans, binding their power to the person's body. However, there's a catch - in time, the human will be overcome by the Chain's power and then thrown into the deepest level of the Abyss. When Oz wakes up in the Abyss he is quickly attacked by hungry Chains, only to be saved by one named Alice - a Chain who appeared just before he was thrown into the prison. Together, the two make a contract and return to the real world, where they are enlisted into the Pandora organization - a group researching both the Abyss and the trio that threw Oz into it. Along with members of Pandora, the duo searches to find Alice's lost memory fragments that are scattered throughout the world, to discover the secrets of the Abyss, and to determine if there's a way their contract can be broken without killing either Oz or Alice.
Like Neo Angelique Abyss, Pandora Hearts features supernatural creatures that the heroes must fight. There is also political intrigue, and characters have to deal with their pasts. Friendships and serving someone also come up in Pandora Hearts.