If you liked the Monochrome Factor anime, the Anime-Planet community thinks you'd like:
It is the early 1920s, and New York City has a problem of evil proportions – demons. With devil worshipping on the rise, foul spirits and monsters have begun to surface, causing fear and panic in their wake. Combating this threat is the Magdalene Order – a group of religious officials charged with exorcising the evil that is spreading throughout the city. Rosette Christopher is a young nun who takes on missions alongside her contracted partner – a young demon named Chrono. Now it is up to this unlikely pair to wield God’s power – and plenty of holy bullets – to destroy the menace in front of them and confront the demons of their past.
In both anime there is alot of action like they have to fight demons to protect humans,also there is a lot of comedy in both of them so if you like monochrome facotor you'd also like Chrono crusade
Naota Nanbada is a boring young boy who leads a boring life in a boring town. His older brother has left for America, and the closest he comes to any excitement is when his deadbeat dad has too much sake. But things change one day when a bizarre girl zooms up to him on a scooter and smacks him in the face with her guitar. What's more, once Naoto returns home he discovers that this strange woman has arrived ahead of him and moved in! Not only does she constantly engage in perverted activities with Naota's father and flirt with the young man himself, but she also claims to be an alien who is searching for the ‘Pirate King.' Now, Naota must learn to live with this new intruder, deal with an odd government agent who sports exceptionally large eyebrows and the mysterious Medical Mechanica, and come to terms with the fact that there are a variety of robots and weapons emerging out of his head - amongst other things. Perhaps boring wasn't so bad after all...
The only real reason I can purpose why Monochrome Factor reminded me so much of FLCL is because of Shirogane advances onto Akira like Haruka's advances on Naoto. Both main character's are dragged into a situation they really didn't want to be apart of but are thanks to these mysterous people that popped up out of no where. Shirogane's little acts of seductions (tiny pranks) he pulls on Akira just to annoy him like Haruka does to Naoto just to get him rilled up. Though the plot to it was a bit confusing and really didn't have a point to it, but I think that if you liked Monochrome Factor you might like FLCL or vice versa.
In a nightmarish Earth, bugs (mushi) have begun to infect humans. Though not hurting their hosts initially, eventually the mushi devour the hosts' dreams, killing them in the process. Humans that are "lucky" enough to have their mushi killed ahead of time become emotionless and thoughtless zombies. In this uncertain time the Mushibune, infected humans who resist their persecution, are up against the Special Environment Preservation Agency, an organization hell-bent on destroying the mushi. Kakkou, SEPA's top agent, has been sent undercover to track down a high school student; but he didn't realize he'd meet and fall for the lovely Shiika instead...
Mushiuta and Monochrome Factor have a remarkably similar feel; they are supernatural tales filled with demons and boring dialogue - and MF adds an absurd amount of chibis to the mix. Not to mention, the strange caterpillar shadow shows up in both anime! I hated both of these, but if you liked one you'd like the other.
Natsume is lonely; he has an ability that separates him from others: he can see and interact with spirits. Soon, however, Natsume discovers that he’s not alone: his grandmother Reiko also had the gift. But things get hectic and possibly dangerous for Natsume when he finds out that he also inherited the 'Book of Friends', a book that contains the names of all the spirits Reiko defeated and subjugated. He finds himself hounded by his grandmother's underlings and, with the help of a 'cat' charm spirit, decides to free them from the Book's shackles, as well as protect the book from those who seek to misuse its power...
Ranmaru is young cop with a dark past. As one of the few survivors of a mindless slaughter in his apartment block, he joins a special unit called TOKKI to avenge his parents. On his first case, the already ghastly murder scene turns to one of terror, as the inhuman killers start to massacre the police. After being saved at the last minute by a secret unit named TOKKO who wield swords instead of guns, Ranmaru's mind is filled with questions and he is determined to find out the answers, no matter what it takes. What are these monsters, and why did they recognize him?
Tokko might be a stretch, but I think the kind of person who likes Monochrome might like it; that is, if you can handle a crapload of blood. Both are relatively supernatural in nature and in my opinion, both suck. Still, they have a similar mood and feel. Try it on for size.