Not many anime have female leads, here is a list of the ones that I know about. This will also include anime, where there are multiple protagonists.
If you know of one, that is not listed, please comment below!
A comprehensive list of every Anime I have taken to completion (or feel I have seen enough) and my thoughts on each. Order was chosen based on personal enjoyment and feelings on the series in question.
These anime are either anime I prefer the dubbed over the subbed or are equal quality dubbed and subbed
Ordered best dub to worst of the best dub
One per franchise is the rule for this list
However some anime I haven't seen the subbed version of...