If you're looking for anime similar to Gintama, you might like these titles. All recommendations are made by Anime-Planet users like you!
Hozuki is the aide to the Great King Enma. Calm and super-sadistic, Hozuki tries to resolve the various problems in Hell, including a rampaging Momotaro and his companions. However, he also likes spending his free time on his hobbies, such as fawning over cute animals and raising ‘Goldfish Flowers.’
Gintama is far more crazy, but both it and Hoozuki no Reitetsu share a similar style of comedy. They're random, fun, and overall just really silly. Gintama can get a little serious and even sad at times while Hoozuki shows no signs of that, but if you're looking for some good comedy and nonsense, you may want to look here.
Space Dandy is a space hunter, someone who is paid to search for new, undiscovered alien species. It's an industry where the prize goes to the person who finds aliens the fastest. Dandy searches unknown planets for strange beings with his companions, QT the worn-out robot and Meow from Betelgeuse. Meanwhile, they're being chased by minions of the Gogol Empire, for reasons that are still a mystery.
The story is set in the Bakumatsu era, at the end of the shoguns' rule over Japan in the middle of the 19th century. The Tokugawa shogunate uses the brainwashing "Heaven's Songs" by the top idols in Shinsengumi to subjugate the country and its people. In this Japan, writing or singing any songs besides the "Heaven's Songs" is a capital offense. Ryōma Sakamoto and the other rockers rise up and change the world with rock 'n' roll for freedom and justice.
The protagonist is an elementary student girl Kohina Ichimatsu who lives alone. One day she summons a fox spirit named Kokkuri-san by a seance game with the same name. He was first intended to possess her, but instead, he decides to manage the household like her mother. The story revolves around a little strange daily life of them with two more other animal spirits, Inugami (dog) and Shigaraki (raccoon dog).
When there's something strange in your neighborhood, who ya gonna call? No, not the Ghostbusters. Call on Panty & Stocking, the two fallen angels Heaven-sent to clear the surface world of Ghosts – creatures spawned from mortals who met gruesome deaths. At least, that's what they'd like you to think. In reality, they're gun-toting, sword-wielding femmes fatales who lay waste not only to the evil of Daten City, but to all its bachelors and candy treats too. With a healthy dollop of collateral damage and full-frontal nudity, they always manage to save the day. If they can be bothered, that is...
Both are hilarious comedy animes that will have you laughing at every episode. These two particularly take a stab at the same kind of humor. Each episode is episodic with something weird and random going on in the crazy world the characters live in, the characters do really weird and random things to either fix or ignore the situation, and weird and random characters are made specifically to be a driving point for the plot for one episode. The main characters seem to get along pretty well and the way they play off each other is always very humorous.