If you liked the Genshiken Nidaime anime, the Anime-Planet community thinks you'd like:
Tsukimi is an otaku and jellyfish enthusiast whose only means of coping with the world is to reject it: she and her friends live in a house they declare a man-free zone, generally avoid 'stylish people', and spend their days blissfully bonding over geeky rituals. As misfortune would have it, their convenient existence is about to be turned on its head by the arrival of Kuranosuke, a seemingly beautiful young woman who is actually a beautiful young man. While he may be strange even by their standards, Kuranosuke embodies everything Tsukimi secretly dreams of being - a princess as ethereal as a floating jellyfish - and promises the kind of mind-boggling adventures only possible when geek meets chic!
Focusing on a group of older female otaku and a crossdressing boy in their midst, both Genshiken Nidaime and Kuragehime are dramatic and funny all at once. Genshiken's earlier seasons are pretty different from Nidaime, so if you have seen either Genshiken Nidaime or Kuragehime, I'd highly recommend the other.