If you're looking for anime similar to Angel Sanctuary, you might like these titles. All recommendations are made by Anime-Planet users like you!
In Japan, there is a disturbing rumor being spread that people's shadows are ripping from their bodies, never to be seen again. For one young man, the frightening nature of this rumor is just beginning to manifest in the form of a nightmarish world that he can't seem to escape from. In this place full of dark minions and demons, he and his friends fight futilely against unknown enemies, only to be brought back to the "real world" as quickly as they left it. Is this real, or a dream? Only one person holds the key to destroying and saving the world as he knows it...
In both Interlude and Angel Sanctuary there is a similar feel of a slice of life series turning into something alien. In Interlude this alienation resolves around the appearance of the existence of two worlds, while in Angel Sanctuary this alien aspect is the existence of angels. The main difference between the two series is humor. Interlude has a healthy amount of humor, while Angel Sanctuary has near to none. Due to this, you will not find any similar characters as well.
Whenever Kippei is at school, he has one thing on his mind: girls. From skipping class to cheesy lines, he'll do anything it takes to reel the ladies in, though he never seems to find the right person. But the bachelor lifestyle is soon to change when young Yuzuyu enters the picture. This five-year-old cutie has been abandoned by her mother, and is to be taken care of by none other than Kippei! Unfortunately for the both of them, Kippei has no experience raising a child, so the learning curve will be quite steep...
If you liked how serious topics were touched in Angel Sanctuary or Ai Baby, forcing the characters to make decisions because of their loved ones and family, then you'd like the other. Angel Sanctuary is way shorter, with only three episodes, but both have a familiar feeling.
Kazuna is a young man with a fairly normal life. He attends high school, lives with his surrogate family, and models for his somber love-interest Yaegashi's paintings. But recently, he has suffered several crippling attacks at the sight of blood -- attacks which leave him incapacitated and out of control. Kazuna must now reunite with his sister who he has not seen in years, and discover the truth behind his family name and vampiric genes, before his bloodthirsty desires destroy himself, or others close to him.
In present day England, a war is being fought. The average citizen does not notice, but vampires are running rampant among the populace, and it's up to the Hellsing organization to contain the bloodsucker threat, using even their own weapons against them. Alucard, a vampire himself, is the best agent the organization has to offer, answering only to Integra Hellsing herself. No one knows much about this mysterious figure fighting against the occult, but things starts to change after he “recruits” a new agent to the establishment...
Both carry a sense of taboo with their story line, playing with religious views and love. For an example, Angel Sanctuary takes a touch of incest (Setsuna loves his sister) and Hellsing is constantly bringing in something to do with religion if not just spirituality in general. Both are great feeds for that more complex, dark side of every anime fan.
In the year 1999, Tokyo has become a battleground as the Seven Dragons of Earth and the Seven Dragons of Heaven fight to determine the fate of the world. The one with the power to decide which way the battle will go is a youth named Kamui Shirou. Will he join the Dragons of Earth and preserve the planet by ending human life, or become a Dragon of Heaven and protect humanity from ruin? The fate of all mankind lies on Kamui's unwilling shoulders as both sides clash to gain dominance. The Dragons on both sides are individuals gifted with superpowers and fated to participate in this final battle, but what end will Kamui choose?
I take it you liked Angel Sanctuary for the dark tones, the violence, the pretty animation, the taboo themes of incest etc. Well, then you'll like X: The Movie. All about people being destined to prevent/cause the apocalypse or some such tragedy, lots of angel wings on show, and gore and dark themes abound. There's no way you won't like X: The Movie if you actually enjoyed Angel Sanctuary, because it's better animated, actually has a complete plot, and is just as cheesy.